Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, as well as the cell walls of fungi and many higher organisms. Glucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat.
How Glucosamine Works ?
It is found naturally in your body. It plays an important role in making glycosaminoglycans and glycoproteins, which are essential building blocks of many parts of your joints, including ligaments, tendons, cartilage and synovial fluid. It’s been suggested that the way these parts of your joint are built and maintained contributes to the development and the progression of osteoarthritis.In clinical studies have found that giving glucosamine can delay the breakdown of cartilage as well as rebuild it.
Methylsulfonylmethane (MSM) is an organosulfur compound with the formula (CH3)2SO2. It is also known by several other names including DMSO2, methyl sulfone, and dimethyl sulfone.This colorless solid features the sulfonyl functional group and is considered relatively inert chemically. It occurs naturally in some primitive plants, is present in small amounts in many foods and beverages. It is also commonly found in the atmosphere above marine areas, where it is used as a carbon source by the airborne bacteria Afipia, and is found distinctively in human melanoma cells.
How MSM Works ?
Methylsulfonylmethane (MSM) is rich in organic sulphur, an important ‘building block’ for healthy bones and joints, and it’s very useful for your immune system. Available evidence from short-term RCTs shows that MSM may have a moderate effect in improving joint pain and swelling as well as general functional wellbeing in people with osteoarthritis. In one trial this effect was greater when MSM was combined with glucosamine.
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Glucosamine and MSM are two dietary supplements that are often taken together to support joint health and relieve joint pain. Glucosamine is a natural compound that is found in cartilage and is essential for joint health. MSM, or methylsulfonylmethane, is a sulfur compound that is also thought to have anti-inflammatory properties.
When taken together in supplement form, glucosamine and MSM may help to reduce inflammation, relieve joint pain, and improve joint flexibility. They are often used to treat conditions like osteoarthritis and other joint-related issues.
It‚s important to note that while these supplements are generally considered safe, they may not be appropriate for everyone. Before taking glucosamine and MSM or any other dietary supplement, it‚s a good idea to talk to your healthcare provider to make sure it is safe for you and won‚t interact with any medications you are taking.
Overall, glucosamine and MSM can be a helpful addition to a joint health and pain management plan, but it‚s important to use them as directed and in conjunction with other recommended treatments.
Glucosamine and MSM are two different compounds that are often combined in joint health supplements, such as the Glucosamine 750 mg MSM 250 mg Tablet. Here‚s a brief overview of the chemistry of each compound:
Glucosamine: Glucosamine is a naturally occurring compound that is found in the cartilage of our joints. It is a type of amino sugar that is produced by the body and is involved in the formation and repair of cartilage. Glucosamine supplements are typically derived from shellfish or made synthetically in a laboratory.
MSM: MSM, or methylsulfonylmethane, is a sulfur-containing compound that is found in many foods, including fruits, vegetables, and grains. It is also found in the human body and is involved in several physiological processes, including inflammation and joint health. MSM supplements are typically made by isolating the compound from natural sources, such as pine trees or algae.
The Glucosamine 750 mg MSM 250 mg Tablet is a dietary supplement that combines these two compounds to support joint health and reduce joint pain. Other ingredients may be included in the tablet to help bind the active ingredients together or improve absorption in the body. It‚s important to read the label carefully and follow the recommended dosage instructions to ensure that you are getting the right amount of each compound for your individual needs.
There have been several clinical studies on the effectiveness of glucosamine and MSM supplements in improving joint health and reducing joint pain. Here are a few examples:
A randomized, double-blind, placebo-controlled study published in the Journal of Research in Medical Sciences in 2011 found that a combination of glucosamine and MSM supplements was effective in reducing pain and improving physical function in patients with knee osteoarthritis.
Another randomized, double-blind, placebo-controlled study published in the journal Osteoarthritis and Cartilage in 2008 found that a combination of glucosamine and MSM supplements improved joint function and reduced pain in patients with knee osteoarthritis.
A 2014 study published in the Journal of Sports Science and Medicine found that a combination of glucosamine and MSM supplements reduced muscle damage and improved recovery time in athletes who engaged in intense exercise.
While these studies suggest that glucosamine and MSM supplements may be effective in improving joint health and reducing joint pain, it‚s important to note that the results may not be the same for everyone. Additionally, more research is needed to fully understand the long-term effects of these supplements and their potential side effects. As always, it‚s a good idea to talk to your healthcare provider before starting any new supplement or medication.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
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