Montelukast is a Leukotriene receptor antagonists. (is used for maintenance treatment of asthma and to relive symptoms of seasonal allergies) It is a selective and orally active leukotrien antagonist that inhibits the cysteinyl leukotrien CysLT1 receptor.
Levocetirizine is a Third – generation non – sedative antihistamine. (is prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever). Levocetirizine, the R – entaiomer of Cetirizine, is a potent and selective antagonist of peripheral H1 – receptors.
It has been demonstrated by recent studies concomitant administration of an antileukotrien (montelukast) and an antihistamine (levocetirizine), shows significantly better symptoms relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone.
Indications:
Montelukast: Add – on therapy for the treatment of patients, 6 years old or older, with mild to moderate asthma in adequately controlled on ‚as required‚ short – acting ß – agonist and inhaled corticosteroids. Monteluakst may offer an alternative to Theophylline as add – on therapy is asthma poorly controlled by short acting ß – agonist and inhaled corticosteroids.
Levocetirizine: All form of skin allergy like food and drug allergy or atopic dermatitis, chronic idiopathic urticaria. Levocetirizine has an affinity 2 – fold higher than that of Cetirizine.
Main Features:
Proplylactic treatment of asthma. Chronic treatment of asthma associated with allergy. Seasonal and perennial rhinitis.
MK Medicine is a leading pcd franchise provider, contract manufacturer and hospital supplier of WHO-GMP certified Levocetirizine Dihydrochloride IP 2.5 mg Montelukast 4 mg Syrup
BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT CHILD HAS NOW OR HAS HAD.
Some medicines may affect how patient‚s works, or other medicine work. If anyone is taking or has recently taken other medicines, including those obtained without a prescription. Such as:
Phenobarbital: Used for treatment of epilepsy.
Pheytoin: Used for treatment of epilepsy.
Rifampicin: Used for treatment of Tuberculosis and some other interactions.
Theophylline, Predisolone, Oral Contraceptives, Terfenadine, Digoxin, Warafin, Thyroid hormones & Sedative hypnotics.
●Thirst was the only adverse experience commonly reported as drug related in 2 – 5 yr olds. Cough was reported as frequently (>1/10) occurring in trials regardless of causalty.
● In older (6 – 14 yr), headache was the most commonly reported drug – related adverse – effect.
● The most commonly reported adverse reactions were headache, asthma and upper respiratory tract infections; however none were significantly different in frequency between the groups.
Disclaimer:To be taken only after consulting with the doctor.
This subsection is not applicable since they are intended for use in children 6 month to 5 years of age; however the following information is relevant to the active ingredients, Montelukast& Levocetirizine.
This medicine is not expected to affect your ability to drive a car or operate machinery Individual response to medication may vary, contain side effects (such as dizziness and drowsiness) that have been reported very rarely with the medicine may affect some patients ability to drive or operate machinery.
This medicine could improve the quality of life of children with allergic rhinitis as well as asthma in addition to being efficacious as immunotherapy in seasonal allergic rhinitis in children aged 2-5 years.
Moreover it has a considerable safety profile, with persistent results.
Oral doses of this medicine has shown efficacy as a preventive treatment for asthma during clinical trials in children aged 2 – 14 years. This combination offers as effective, well tolerated and convient treatment option for children with asthma and allergies.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.