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Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting.

Ondansetron is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment.

Ondansetron may be used for purposes not listed in this medication guide.

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1 Vial x 10

You should not use ondansetron if you are also using apomorphine (Apokyn).

You should not use ondansetron if you are allergic to it or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi).

Before taking ondansetron, tell your doctor if you have liver disease, or a personal or family history of Long QT syndrome.

Ondansetron orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

Serious side effects of ondansetron include blurred vision or temporary vision loss (lasting from only a few minutes to several hours), slow heart rate, trouble breathing, anxiety, agitation, shivering, feeling like you might pass out, and urinating less than usual or not at all. Stop taking this medicine and call your doctor at once if you have any of these side effects. Ondansetron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Call your doctor at once if you have:

  • severe constipation, stomach pain, or bloating;

  • headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;

  • fast or pounding heartbeats;

  • jaundice (yellowing of the skin or eyes);

  • blurred vision or temporary vision loss (lasting from only a few minutes to several hours);

  • high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

Common ondansetron side effects may include:

  • diarrhea or constipation;

  • headache;

  • drowsiness; or

  • tired feeling.

Ondansetron tablets are indicated for the prevention of nausea and vomiting associated with:

 

  • highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2.
  • initial and repeat courses of moderately emetogenic cancer chemotherapy.
  • radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.

Ondansetron tablets are also indicated for the prevention of postoperative nausea and/or vomiting.

You should not use ondansetron if:

  • you are also using apomorphine (Apokyn); or

  • you are allergic to ondansetron or similar medicines (dolasetron, granisetron, palonosetron).

To make sure ondansetron is safe for you, tell your doctor if you have:

  • liver disease;

  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

  • congestive heart failure, slow heartbeats;

  • a personal or family history of long QT syndrome; or

  • a blockage in your digestive tract (stomach or intestines).

Ondansetron is not expected to harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Ondansetron is not approved for use by anyone younger than 4 years old.

Ondansetron orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.