Ramipril 2.5 mg Hydrochlorothiazide 12.5 mg Tablet

Do not take ramipril - hydrochlorothiazide if you:

• are allergic to ramipril, hydrochlorothiazide, or any ingredients of the medication
• are allergic to any other ACE inhibitor (e.g., enalapril, lisinopril, captopril)
• are allergic to sulfonamide medications (e.g., sulfamethoxazole)
• are pregnant or breast-feeding
• are not passing urine
• have had angioedema (a serious allergic reaction which causes the area around the throat and tongue to swell)
• have low blood pressure
• have narrowing of arteries in the kidneys
• are receiving dialysis
• have severely reduced liver function
• have severely reduced kidney function
• have uncorrected potassium, sodium or calcium levels in the blood
• have diabetes and/or kidney disease and are taking the medication aliskiren

• dizziness, lightheadedness, or fainting when rising from a lying or sitting position
• fast heartbeat, irregular heartbeat, or palpitations
• joint pain
• low blood pressure (dizziness, lightheadedness)
• numbness or tingling in the hands, feet, or lips
• signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
• signs of bleeding (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don‚t stop bleeding)
• signs of changed potassium levels (e.g., irregular heartbeat, muscle weakness, general feeling unwell)
• signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
• signs of kidney problems (e.g., decreased urination, nausea, vomiting, swelling of legs, hands, fatigue)
• signs of liver damage (abdominal pain, fever, nausea, vomiting, loss of appetite, or yellowing of the skin or eyes)
• signs of low blood pressure such as dizziness, lightheadedness, or fainting
• signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)
• skin rash (with or without itching), fever, or joint pain
• swelling of hands, ankles or feet
• symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
• symptoms of increased pressure in the eyes (e.g., decreased or blurred vision, eye pain, red eye, swelling of the eye)
• sore throat and fever
• swelling of the hands, feet, or ankles

Stop taking the medication and seek immediate medical attention if any of the following occur:

• abdominal pain (with or without nausea or vomiting)
• signs of an allergic reaction, including angioedema (shortness of breath or difficulty breathing; hives; swelling of the eyes, mouth, lips, or throat)
• signs of a heart attack (e.g., chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating)
• signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
• signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.