Lornoxicam 8 mg Paracetamol 325 mg Tablet
Lornoxicam is a new non steroidal anti-inflammatory medication of the oxicam class with analgesic and antipyretic properties. Lornoxicam Paracetamol was also as effective as other NSAIDs in relieving symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis etc.
Paracetamol or acetaminophen USAN, is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used for the relief of headaches and other minor aches and pains and is a major ingredient in numerous cold and flu remedies. In combination with opioid analgesics, paracetamol can also be used in the management of more severe pain such as post-surgical pain and providing palliative care in advanced cancer patients.
●Muscle pain and Musculo skeletal pain.
●Low back pain.
●Post operative pain.
●Arthritis. [Osteo & Rhumatoid Arthritis].
●Ankylosing spondylitis.
●Acute Sciatica.
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Most of adverse reactions observed in clinical trials were of a mild and transient nature. The most commonly seen adverse reactions in clinical trials of the tablet formulation were gastrointestinal and also adverse reaction have been reported for cephalosporin sensitive person and also in some cases somnolence, nasopharyngitis, fatigue, dry mouth and pharyngitis, and most were mild to moderate in intensity.
Lornoxicam inhibits prostaglandin biosynthesis by blocking the enzyme Cyclo- oxygenase. Lornoxicam inhibits both isoforms in the same concentration range, that is, Balanced COX-1 Inhibition & COX-2 inhibition through that it‚s a safest pain killer. It is distinguished from established oxicams by a relatively short elimination half-life (3 to 5 hours), which may be advantageous from a tolerability standpoint. The absolute bioavailability of Lornoxicam is 90-100% and no first pass effect was observed.
Paracetamol is usually classified along with nonsteroidal anti-inflammatory drugs (NSAID), Like all drugs of this class, its main mechanism of action is the inhibition of Cyclo oxygenase (COX). Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity. It does not possess anti-inflammatory activity. Paracetamol is thought to produce analgesia through a central inhibition of prostaglandin synthesis.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
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