Diclofenac Potassium is a non-steroidal anti-inflammatory agent (NSAIDs) with antipyretic and analgesic actions.
Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15 used in the prevention of pain and swelling.
● For the treatment of primary dysmenorrhea.
● For the treatment of mild to moderate pain.
● For the relief from the signs and symptoms of osteoarthritis.
● For the relief from the signs and symptoms of rheumatoid arthritis.
● Chronic inflammation.
● Headaches, muscle and joint pain.
● Serious diseases like cancer and heart disease.
● Superficial thrombophlebitis.
● Postoperative & traumatic swelling.
● Acute or chronic ear, nose or throat disorder.
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Diclofenac sodium and Serratiopeptidase is contraindicated in patients with active GI bleeding or perforations, asthma, renal or hepatic disorders, hypertension, porphyria, peri-operative pain in CABG surgery patients and bleeding disorders.
● Skin rash
● Diarrhea
● Gastrointestinal disturbance
● Noseblee
● Dizziness
Diclofenac Potassium:
Diclofenac Potassium is an acetic acid non-steroidal anti-inflammatory drug (NSAIDs) with analgesic and antipyretic properties. Diclofenac Potassium inhibits the production of prostaglandins by inhibiting COX-1 and COX-2 pathways thereby exhibiting anti- inflammatory effects.
Pharmacokinetic:
Absorption: Well absorbed following oral administration.
Distribution: widely distributed in animals. Plasma protein binding exhibited is >99%.
Elimination: hepatic metabolism leads to elimination through urine.
Serratiopeptidase:
Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15. Serratiopeptidase has powerful anti-inflammatory properties and is particularly useful for post-traumatic swelling, fibrocystic breast disease and bronchitis. It is able to digest dead tissue, blood clots, cysts, and arterial plaques.
Pharmacokinetic:
Absorption: On oral administration, serratiopeptidase is absorbed in GI tract.
Distribution: Distributed throughout the body tissues, unchanged via systemic circulation. It reaches in higher concentration in inflamed tissues.
Serratiopeptidase levels in inflammatory exudates rises gradually with decline in blood levels indicating that serratiopeptidase is quite rapidly transferred to the site of inflammation.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
Aceclofenac 200 mg Sustained Release Tablet