Ciprofloxacin 250 mg Tinidazole 300 mg Tablet
Ciprofloxacin(500 mg)
Uses
Ciprofloxacin is used in the treatment of bacterial infections and tuberculosis (TB)
How it works
Ciprofloxacin is an antibiotic. It kills bacteria by inhibiting the DNA replication.
Tinidazole(600 mg)
Uses
Tinidazole is used in the treatment of diarrhoea and bacterial infections
How it works
Tinidazole is an antibiotic. It kills the bacteria that cause infections.
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10x10 (Blister)
Special Precautions
Renal impairment, history of seizures; ensure adequate hydration & urinary output; avoid alcohol ingestion. Not recommended for use in lactation and pregnancy. Not recommended for children. Patients with CNS disorders. Inadequate water intake during treatment may cause crystalluria.
Common side effects of Ciprofloxacin
Vomiting, Nausea, Nervousness, Nightmare, Abnormal dreams, Anxiety, Confusion, Diarrhoea, Dizziness, Headache, Heartburn, Insomnia, Restlessness, Stomach pain, Vaginal itching, Vaginal discharge.
Common side effects of Tinidazole
Ankle swelling, Headache, Dizziness, Angioedema (swelling of deeper layers of skin), Convulsion, Swelling of mouth, Hoarseness of voice, Facial swelling, Shortness of breath, Vomiting, Weakness, Allergic reaction, Lip swelling, Nausea, Abdominal pain, Skin irritation, Coating on tongue, Numbness, Difficulty in swallowing, Loss of appetite, Stomach cramp, Fatigue, Acne-like rash, Dry skin, Altered taste, Urticaria, Stomach upset, Constipation, Limb swelling
Antacids, sucralfate, calcium, Fe & Zn prep reduce absorption of ciprofloxacin. Concurrent use with ciclosporin may lead to transient increases in serum creatinine levels. Increases plasma levels and elimination half-life of theophylline; potentiates oral anticoagulant effects; disulfiram-like effect with alcohol. May affect metabolism of caffeine resulting in reduced clearance of caffeine.
Ciprofloxacin is bactericidal against enteropathogens like Shigella, Salmonella, E coli, C jejuni, Vibrio cholerae etc. It acts by inhibition of DNA synthesis. Tinidazole is a potent anaerobicide. It is also effective against Entameba & Giardia. It acts by damaging DNA strands. This combination has the advantage of being effective against both bacteria & protozoa. Entameba requires normal faecal flora for its survival; ciprofloxacin kills the pathogenic intestinal bacteria & alters intestinal flora, & tinidazole directly eradicates Entameba. This combination can also be used in other systemic infections caused by susceptible organisms.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
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